| Montevideo, Uruguay | 11/06 14:00 | 25 | [181] Vilella Martinez, Mario v Filip C Jianu [447] | 6-2,5-7,6-4 | |
| Challenger Guayaquil | 10/29 23:00 | 25 | [179] Vilella Martinez, Mario v Quiroz, Roberto [268] | 7-6,5-7,2-6 | |
| Challenger Lima | 10/24 18:05 | 26 | [131] Federico Coria v Vilella Martinez, Mario [179] | 6-2,6-1 | |
| Challenger Lima | 10/22 16:30 | 25 | [347] Pedro Sakamoto v Vilella Martinez, Mario [179] | 6-4,3-6,6-7 | |
| Santo Domingo, Dominican Republic | 10/10 23:00 | 26 | [181] Vilella Martinez, Mario v Alejandro Tabilo [224] | 6-3,0-6,3-6 | |
| Santo Domingo, Dominican Republic | 10/08 17:00 | 25 | [181] Vilella Martinez, Mario v Hamou, Maxime [371] | 6-2,6-1 | |
| Florence, Italy | 09/27 09:00 | 27 | [205] Marco Trungelliti v Vilella Martinez, Mario [191] | 4-6,6-3,7-6 | |
| Florence, Italy | 09/26 11:10 | 26 | [177] Horansky, Filip v Vilella Martinez, Mario [191] | 1-6,1-6 | |
| Florence, Italy | 09/25 11:30 | 25 | [191] Vilella Martinez, Mario v Martin Klizan [121] | Retired | |
| Florence, Italy | 09/24 10:50 | 24 | [340] Gimeno-Traver, Daniel v Vilella Martinez, Mario [191] | 6-7,2-6 | |
| Challenger Biella | 09/19 11:30 | 26 | [191] Vilella Martinez, Mario v Andrea Collarini [219] | 7-6,4-6,2-6 | |
| Challenger Biella | 09/18 08:00 | 25 | [191] Vilella Martinez, Mario v Raul Brancaccio [283] | 6-1,6-4 | |
| Challenger Seville | 09/12 11:00 | 26 | [190] Vilella Martinez, Mario v Garcia-Lopez, Guillermo [150] | 6-1,6-7,4-6 | |
| Challenger Seville | 09/11 16:55 | 25 | [190] Vilella Martinez, Mario v Javier Barranco Cosano [298] | 7-6,7-6 | |
| Challenger Mallorca | 08/28 08:00 | 25 | [342] Botic Van De Zandschulp v Vilella Martinez, Mario [202] | Retired | |
| US Open, New York, USA | 08/23 18:30 | 46 | [202] Vilella Martinez, Mario v Jannik Sinner [131] | 6-7,0-6 | |
| US Open, New York, USA | 08/22 17:25 | 45 | [202] Vilella Martinez, Mario v Akira Santillan [242] | 6-7,6-4,6-2 | |
| US Open, New York, USA | 08/20 19:25 | 44 | [117] Taro Daniel v Vilella Martinez, Mario [202] | 6-7,7-6,4-6 | |
| Augsbourg, Allemagne | 08/08 10:35 | 26 | [313] Lenz, Julian v Vilella Martinez, Mario [207] | 6-1,6-2 | |
| Augsbourg, Allemagne | 08/06 12:55 | 25 | [343] Peter Heller v Vilella Martinez, Mario [207] | 2-6,2-6 | |
| Challenger Liberec | 07/30 08:00 | 24 | [366] Zsombor Piros v Vilella Martinez, Mario [208] | 6-1,4-6,6-4 | |
| Challenger Prague | 07/28 13:00 | 29 | [428] Chun Hsin Tseng v Vilella Martinez, Mario [266] | 4-6,2-6 | |
| Challenger Prague | 07/27 11:20 | 28 | [266] Vilella Martinez, Mario v Carlos Taberner [335] | 7-5,6-2 | |
| Challenger Prague | 07/26 13:30 | 27 | [266] Vilella Martinez, Mario v Lorenzo Giustino [137] | 6-0,7-6 | |
| Challenger Prague | 07/25 11:35 | 26 | [266] Vilella Martinez, Mario v Balazs, Attila [141] | 6-4,6-3 | |
| Challenger Prague | 07/24 11:45 | 25 | [202] Nedovyesov, Aleksandr v Vilella Martinez, Mario [266] | 2-6,1-6 | |
| Challenger Prague | 07/22 14:30 | 24 | Martin Damm v Vilella Martinez, Mario | 1-6,1-6 | |
| Challenger Perugia | 07/09 10:20 | 25 | [160] Alessandro Giannessi v Vilella Martinez, Mario [269] | 6-7,6-2,6-3 | |
| Challenger Perugia | 07/08 12:20 | 24 | [269] Vilella Martinez, Mario v Gimeno-Traver, Daniel [244] | 6-3,5-7,6-2 | |
| Milan, Italy | 06/25 14:40 | 25 | [329] Cuevas, Martin v Vilella Martinez, Mario [262] | 6-3,2-6,6-4 |