| NCAAB | 11/08 00:00 | - | Guilford Quakers v Davidson | L | 64-87 | |
| NCAAB | 12/08 00:00 | - | High Point v Guilford Quakers | L | 64-59 | |
| NCAAB | 11/13 00:00 | - | UNC Wilmington v Guilford Quakers | L | 77-68 | |
| NCAAB | 02/28 20:00 | 3 | Guilford Quakers v Roanoke Maroons | L | 66-73 | |
| NCAAB | 02/22 19:00 | - | Guilford Quakers v Randolph Macon Yellow Jackets | W | 63-54 | |
| NCAAB | 02/15 20:00 | - | Guilford Quakers v Hampden–Sydney Tigers | W | 93-68 | |
| NCAAB | 02/13 00:00 | - | Virginia Lynchburg Dragons v Guilford Quakers | W | 60-75 | |
| NCAAB | 02/08 19:00 | - | Guilford Quakers v Eastern Mennonite Royals | W | 95-50 | |
| NCAAB | 02/06 00:00 | - | Guilford Quakers v Ferrum Panthers | L | 53-60 | |
| NCAAB | 02/01 19:00 | - | Washington & Lee Generals v Guilford Quakers | L | 90-61 | |
| NCAAB | 01/29 22:00 | - | Guilford Quakers v Randolph Wildcats | W | 72-39 | |
| NCAAB | 01/25 20:00 | - | Guilford Quakers v Shenandoah Hornets | W | 85-52 | |
| NCAAB | 01/18 21:30 | - | Randolph Macon Yellow Jackets v Guilford Quakers | L | 64-39 | |
| NCAAB | 01/16 00:00 | - | Emory And Henry Wasps v Guilford Quakers | W | 87-99 | |
| NCAAB | 01/11 20:00 | - | Guilford Quakers v Bridgewater Eagles | W | 80-58 | |
| NCAAB | 01/08 00:00 | - | Ferrum Panthers v Guilford Quakers | L | 68-65 | |
| NCAAB | 01/04 19:00 | - | Hampden–Sydney Tigers v Guilford Quakers | L | 54-52 | |
| NCAAB | 12/30 21:00 | - | Emory Eagles v Guilford Quakers | W | 69-70 | |
| NCAAB | 12/29 19:00 | - | La Grange Panthers v Guilford Quakers | W | 67-84 | |
| NCAAB | 12/07 20:00 | - | Guilford Quakers v Virginia Wesleyan Blue Marlins | L | 57-64 | |
| NCAAB | 12/05 00:00 | - | Roanoke Maroons v Guilford Quakers | W | 58-74 | |
| NCAAB | 11/30 19:00 | - | Eastern Mennonite Royals v Guilford Quakers | W | 52-71 | |
| NCAAB | 11/26 22:00 | - | Guilford Quakers v Methodist Monarchs | W | 62-60 | |
| NCAAB | 11/23 19:00 | - | Guilford Quakers v Berry Vikings | W | 73-56 | |
| NCAAB | 11/21 00:00 | - | Guilford Quakers v Averett Cougars | W | 76-61 | |
| NCAAB | 11/17 21:00 | - | Guilford Quakers v NC Wesleyan Battling Bishops | W | 67-50 | |
| NCAAB | 11/16 00:30 | - | Guilford Quakers v Mary Hardin-Baylor Crusaders | W | 60-52 | |
| NCAAB | 11/14 00:00 | - | Guilford Quakers v Greensboro College | W | 87-75 | |
| NCAAB | 11/09 21:00 | - | Guilford Quakers v Emory Eagles | L | 67-89 | |
| NCAAB | 11/11 12:00 | - | Coastal Carolina v Guilford Quakers | L | 76-49 |