| NCAAF | 12/16 00:00 | 1 | Cortland v North Central Cardinals | L | 38-37 | |
| NCAAF | 12/09 20:30 | 2 | Wartburg Knights v North Central Cardinals | W | 27-34 | |
| NCAAF | 12/02 18:00 | 3 | UW–La Crosse v North Central Cardinals | W | 42-55 | |
| NCAAF | 11/25 18:00 | 8 | North Central Cardinals v Trinity Tigers | W | 71-28 | |
| NCAAF | 11/18 18:00 | 7 | North Central Cardinals v Belhaven Blazers | W | 65-0 | |
| NCAAF | 11/11 18:00 | 1 | Augustana College v North Central Cardinals | W | 17-61 | |
| NCAAF | 11/04 18:00 | 1 | North Central Cardinals v Illinois Wesleyan Titans | W | 83-26 | |
| NCAAF | 10/28 18:00 | 1 | North Park Vikings v North Central Cardinals | W | 0-56 | |
| NCAAF | 10/21 18:00 | 1 | North Central Cardinals v Washington Bears | W | 49-3 | |
| NCAAF | 10/14 18:00 | 1 | Millikin Big Blue v North Central Cardinals | W | 3-75 | |
| NCAAF | 10/07 23:00 | 1 | North Central Cardinals v Carroll Pioneers | W | 69-24 | |
| NCAAF | 09/30 18:00 | 1 | Wheaton Thunder v North Central Cardinals | W | 35-54 | |
| NCAAF | 09/23 19:00 | 1 | Elmhurst Bluejays v North Central Cardinals | W | 6-59 | |
| NCAAF | 09/16 18:00 | 1 | North Central Cardinals v Carthage Red Men | W | 70-0 | |
| NCAAF | 09/02 18:00 | 1 | Robert Morris (Il) Eagles v North Central Cardinals | W | 7-41 | |
| NCAAF | 12/17 00:00 | 1 | Mount Union v North Central Cardinals | W | 21-28 | |
| NCAAF | 12/10 20:30 | 2 | North Central Cardinals v Mary Hardin Baylor Crusaders | W | 49-14 | |
| NCAAF | 12/03 18:00 | 3 | North Central Cardinals v Ithaca Bombers | W | 48-7 | |
| NCAAF | 11/26 18:00 | 8 | North Central Cardinals v Carnegie Mellon Tartans | W | 28-7 | |
| NCAAF | 11/19 18:00 | 7 | North Central Cardinals v Lake Forest Foresters | W | 50-0 | |
| NCAAF | 11/12 19:00 | 1 | North Central Cardinals v Augustana College | W | 63-3 | |
| NCAAF | 11/05 18:00 | 1 | Illinois Wesleyan Titans v North Central Cardinals | W | 3-68 | |
| NCAAF | 10/29 18:00 | 1 | North Central Cardinals v North Park Vikings | W | 59-0 | |
| NCAAF | 10/22 18:00 | 1 | Washington Bears v North Central Cardinals | W | 0-31 | |
| NCAAF | 10/15 18:00 | 1 | North Central Cardinals v Millikin Big Blue | W | 65-0 | |
| NCAAF | 10/08 18:00 | 1 | Carroll Pioneers v North Central Cardinals | W | 0-73 | |
| NCAAF | 10/01 23:00 | 1 | North Central Cardinals v Wheaton Thunder | W | 33-20 | |
| NCAAF | 09/24 18:00 | 1 | North Central Cardinals v Elmhurst Bluejays | W | 76-6 | |
| NCAAF | 09/17 18:00 | 1 | Carthage Red Men v North Central Cardinals | W | 7-59 | |
| NCAAF | 09/10 17:00 | 1 | Wabash Little Giants v North Central Cardinals | W | 12-56 |