| Acapulco, Mexico | 02/27 22:00 | 25 | [91] Varvara Lepchenko v Kristina Mladenovic [30] | 2-6,3-6 | |
| ITF Women Midland | 02/03 15:00 | 27 | Katherine Sebov v Varvara Lepchenko | 3-6,6-4,7-6 | |
| ITF Women Midland | 02/02 17:00 | 26 | Katarzyna Kawa v Varvara Lepchenko | 2-6,4-6 | |
| ITF Women Midland | 02/02 00:00 | 25 | Hibi, Mayo v Varvara Lepchenko | 6-4,5-7,4-6 | |
| Australian Open 2017 Women | 01/18 00:00 | 24 | [88] Varvara Lepchenko v Duan, Ying-Ying [87] | 1-6,6-3,8-10 | |
| Australian Open 2017 Women | 01/16 00:00 | 23 | [22] Bertens, Kiki v Varvara Lepchenko [86] | 5-7,6-7 | |
| Sydney, Australie, Qualifications | 01/06 04:35 | 45 | Varvara Lepchenko v Duan, Ying-Ying | 1-6,4-6 | |
| WTA Auckland | 01/04 08:05 | 26 | [89] Varvara Lepchenko v Caroline Wozniacki [19] | 3-6,3-6 | |
| WTA Auckland | 01/03 04:05 | 25 | Arina Rodionova v Varvara Lepchenko | 3-6,4-6 | |
| WTA Luxembourg | 10/19 16:10 | 26 | [11] Kvitova, Petra v Varvara Lepchenko [90] | 4-6,6-2,6-1 | |
| WTA Luxembourg | 10/17 17:20 | 25 | [90] Varvara Lepchenko v Pironkova, Tsvetana [65] | 6-1,3-6,6-1 | |
| WTA Hong Kong | 10/10 04:10 | 25 | [49] Alize Cornet v Varvara Lepchenko [91] | 6-3,6-2 | |
| WTA Beijing Qual | 10/01 07:45 | 46 | [56] Katerina Siniakova v Varvara Lepchenko [87] | 2-6,7-6,7-6 | |
| WTA Beijing Qual | 09/30 04:55 | 45 | Aliaksandra Sasnovich v Varvara Lepchenko | 1-6,6-3,3-6 | |
| Wuhan, China | 09/25 06:00 | 24 | Varvara Lepchenko v Safarova, Lucie | 5-7,3-6 | |
| WTA Tokyo | 09/19 07:20 | 25 | Varvara Lepchenko v Monica Puig | 0-6,3-6 | |
| WTA Tokyo | 09/16 03:00 | 27 | Varvara Lepchenko v Shuai Zhang | 7-6,1-6,3-6 | |
| WTA Tokyo | 09/14 03:45 | 26 | Larsson, Johanna v Varvara Lepchenko | 2-6,6-3,4-6 | |
| WTA Tokyo | 09/12 07:10 | 25 | Ozaki, Risa v Varvara Lepchenko | 0-6,2-6 | |
| US Open 2016 Women | 09/03 18:15 | 25 | Ana Konjuh v Varvara Lepchenko | 6-3,3-6,6-2 | |
| US Open 2016 Women | 09/01 22:20 | 24 | Varvara Lepchenko v Bacsinszky, Timea | 6-4,4-6,6-4 | |
| US Open 2016 Women | 08/30 20:30 | 23 | Peng, Shuai v Varvara Lepchenko | 6-4,6-7,3-6 | |
| WTA Montreal | 07/28 23:10 | 26 | Varvara Lepchenko v Konta, Johanna | 3-6,2-6 | |
| WTA Montreal | 07/26 23:00 | 25 | Varvara Lepchenko v Broady, Naomi | 6-4,3-6,6-3 | |
| WTA Montreal Qual | 07/24 16:35 | 45 | Varvara Lepchenko v Kudryavtseva, Alla | 2-6,2-6 | |
| WTA Montreal Qual | 07/23 21:15 | 44 | Varvara Lepchenko v Klepac, Andreja | 6-1,6-1 | |
| Wimbledon Women | 06/30 14:15 | 24 | Varvara Lepchenko v Angelique Kerber | 1-6,4-6 | |
| Wimbledon Women | 06/27 15:00 | 23 | Pereira, Teliana v Varvara Lepchenko | 7-5,6-7,2-6 | |
| Wimbledon Women | 06/30 10:30 | 23 | Muguruza, Garbine v Varvara Lepchenko | 6-4,6-1 | |
| Wimbledon Women | 06/25 15:10 | 24 | Caroline Garcia v Varvara Lepchenko | 7-5,6-3 |