| NCAAF | 11/25 19:00 | 8 | Harding Bisons v Central Missouri Mules | L | 35-34 | |
| NCAAF | 11/18 19:00 | 7 | Central Missouri Mules v Henderson State Reddies | W | 56-14 | |
| NCAAF | 11/11 18:00 | 1 | Blue Tigers v Central Missouri Mules | W | 27-63 | |
| NCAAF | 11/04 18:00 | 1 | Central Missouri Mules v Fort Hays State University Tigers | W | 47-28 | |
| NCAAF | 10/28 19:00 | 1 | Missouri Southern Lions v Central Missouri Mules | W | 21-42 | |
| NCAAF | 10/21 18:30 | 1 | Central Missouri Mules v Emporia State | W | 77-27 | |
| NCAAF | 10/14 19:00 | 1 | Northeastern State Riverhawks v Central Missouri Mules | W | 24-63 | |
| NCAAF | 10/07 18:00 | 1 | Central Missouri Mules v Nebraska Kearney | W | 38-14 | |
| NCAAF | 09/30 18:00 | 1 | Central Missouri Mules v Northwest Missouri | W | 41-38 | |
| NCAAF | 09/23 18:00 | 1 | Washburn Ichabods Football v Central Missouri Mules | W | 28-58 | |
| NCAAF | 09/16 18:00 | 1 | Central Missouri Mules v Pittsburg State Gorillas | L | 37-38 | |
| NCAAF | 09/09 18:00 | 1 | Central Missouri Mules v Central Oklahoma | W | 41-17 | |
| NCAAF | 09/01 00:00 | 1 | Missouri Western Griffons v Central Missouri Mules | W | 38-45 | |
| NCAAF | 11/12 20:00 | 1 | Central Oklahoma v Central Missouri Mules | L | 13-10 | |
| NCAAF | 11/05 18:00 | 1 | Central Missouri Mules v Missouri Western Griffons | W | 40-37 | |
| NCAAF | 10/29 18:00 | 1 | Central Missouri Mules v Blue Tigers | W | 61-14 | |
| NCAAF | 10/22 18:00 | 1 | Fort Hays State University Tigers v Central Missouri Mules | L | 27-14 | |
| NCAAF | 10/15 18:30 | 1 | Central Missouri Mules v Missouri Southern Lions | W | 20-17 | |
| NCAAF | 10/08 18:00 | 1 | Emporia State v Central Missouri Mules | L | 44-27 | |
| NCAAF | 10/01 18:00 | 1 | Central Missouri Mules v Northeastern State Riverhawks | W | 35-13 | |
| NCAAF | 09/24 18:00 | 1 | Nebraska Kearney v Central Missouri Mules | L | 38-6 | |
| NCAAF | 09/17 18:30 | 1 | Northwest Missouri v Central Missouri Mules | L | 24-7 | |
| NCAAF | 09/09 00:00 | 1 | Central Missouri Mules v Washburn Ichabods Football | L | 32-40 | |
| NCAAF | 09/02 00:00 | 1 | Pittsburg State Gorillas v Central Missouri Mules | L | 21-10 | |
| NCAAF | 11/13 19:00 | 1 | Central Missouri Mules v Central Oklahoma | W | 30-29 | |
| NCAAF | 11/06 18:00 | 1 | Missouri Western Griffons v Central Missouri Mules | L | 59-28 | |
| NCAAF | 10/30 19:00 | 1 | Blue Tigers v Central Missouri Mules | W | 35-77 | |
| NCAAF | 10/23 18:30 | 1 | Central Missouri Mules v Fort Hays State University Tigers | L | 17-21 | |
| NCAAF | 10/16 21:00 | 1 | Missouri Southern Lions v Central Missouri Mules | L | 30-28 | |
| NCAAF | 10/09 18:00 | 1 | Central Missouri Mules v Emporia State | W | 45-38 |