Stadium: Saluki Stadium Round: 1
Home Manager: Nick Hill Away Manager: Curt Mallory
| NCAAF | 2021/11/13 18:00 | Southern Illinois v Indiana State | L | 47-21 |
| NCAAF | 2019/11/02 17:00 | Southern Illinois v Indiana State | L | 23-14 |
| NCAAF | 2018/10/20 19:00 | Southern Illinois v Indiana State | W | 21-24 |
| NCAAF | 2017/10/21 19:00 | Indiana State v Southern Illinois | L | 24-45 |
| NCAAF | 2023/11/11 18:00 | Western Illinois v Indiana State | W | 6-27 |
| NCAAF | 2023/11/04 17:00 | Youngstown State v Indiana State | L | 19-7 |
| NCAAF | 2023/10/28 18:00 | Indiana State v North Dakota | L | 33-36 |
| NCAAF | 2023/10/21 17:00 | South Dakota v Indiana State | L | 17-3 |
| NCAAF | 2023/10/14 19:00 | Indiana State v Illinois State | L | 7-44 |
| NCAAF | 2023/10/07 23:00 | Northern Iowa v Indiana State | L | 27-20 |
| NCAAF | 2023/09/30 23:00 | Indiana State v Murray State | L | 28-30 |
| NCAAF | 2023/09/16 18:00 | Indiana State v Ball State | L | 7-45 |
| NCAAF | 2023/11/11 20:30 | Southern Illinois v DAKOTA DU NORD ETAT DU BISON | L | 10-34 |
| NCAAF | 2023/11/04 18:00 | South Dakota v Southern Illinois | L | 14-7 |
| NCAAF | 2023/10/28 20:00 | Southern Illinois v Western Illinois | W | 63-0 |
| NCAAF | 2023/10/21 19:00 | South Dakota State v Southern Illinois | L | 17-10 |
| NCAAF | 2023/10/14 19:00 | Southern Illinois v Murray State | W | 27-6 |
| NCAAF | 2023/10/07 22:00 | Southern Illinois v Youngstown State | L | 3-31 |
| NCAAF | 2023/09/30 21:00 | Missouri State v Southern Illinois | W | 20-33 |
| NCAAF | 2023/09/16 23:00 | Southern Illinois v SE Missouri State | W | 26-25 |