Home History
| NFL | 2016/10/30 17:00 | Nouvelle-Angleterre v BUF Bills | L | 41-25 |
| NFL | 2016/10/23 17:00 | BUF Bills v MIA Dolphins | L | 25-28 |
| NFL | 2016/10/16 17:00 | SF 49ers v BUF Bills | W | 16-45 |
| NFL | 2016/10/09 20:25 | BUF Bills v LA Rams | W | 30-19 |
| NFL | 2016/10/02 17:00 | BUF Bills v Nouvelle-Angleterre | W | 16-0 |
| NFL | 2016/09/25 17:00 | Arizona v BUF Bills | W | 18-33 |
| NFL | 2016/09/16 00:25 | NY Jets v BUF Bills | L | 37-31 |
| NFL | 2016/09/11 17:00 | BUF Bills v BAL Ravens | L | 7-13 |
Away History
| NFL | 2016/10/30 17:00 | Seattle v Nouvelle-Orléans | L | 20-25 |
| NFL | 2016/10/24 00:30 | Seattle v Arizona | D | 6-6 |
| NFL | 2016/10/16 20:25 | Atlanta v Seattle | W | 24-26 |
| NFL | 2016/10/02 17:00 | Seattle v NY Jets | W | 27-17 |
| NFL | 2016/09/25 20:05 | SF 49ers v Seattle | W | 18-37 |
| NFL | 2016/09/18 20:05 | Seattle v LA Rams | L | 3-9 |
| NFL | 2016/09/11 20:05 | MIA Dolphins v Seattle | W | 10-12 |
| NFL pré-saison | 2016/09/02 02:00 | Seattle v Las Vegas | W | 23-21 |