Stadium: Knapp Center
Home Manager: Darian DeVries Away Manager: Luke Yaklich
| NCAAB | 2022/12/01 01:00 | Missouri State v Illinois Chicago Flames | L | 66-51 |
| NCAAB | 2022/11/27 00:00 | Illinois Chicago Flames v Wisc Green Bay | W | 78-64 |
| NCAAB | 2022/11/22 21:00 | Illinois Chicago Flames v Holy Cross | W | 89-66 |
| NCAAB | 2022/11/21 21:00 | Stonehill v Illinois Chicago Flames | W | 71-77 |
| NCAAB | 2022/11/19 22:00 | Illinois Chicago Flames v Fordham | L | 65-79 |
| NCAAB | 2022/11/15 01:00 | Jacksonville State Gamecocks v Illinois Chicago Flames | W | 60-67 |
| NCAAB | 2022/11/12 01:00 | Loyola Chicago v Illinois Chicago Flames | L | 70-63 |
| NCAAB | 2022/11/08 01:00 | Trinity Christian Trolls v Illinois Chicago Flames | W | 48-82 |
| NCAAB | 2022/12/01 00:00 | Drake v Indiana State | L | 73-75 |
| NCAAB | 2022/11/26 23:00 | UL Lafayette v Drake | W | 64-76 |
| NCAAB | 2022/11/22 01:00 | Drake v Tarleton State | W | 71-64 |
| NCAAB | 2022/11/20 22:45 | Drake v Wyoming | W | 61-56 |
| NCAAB | 2022/11/18 18:00 | Buffalo v Drake | W | 72-80 |
| NCAAB | 2022/11/15 01:00 | Wofford v Drake | W | 72-80 |
| NCAAB | 2022/11/10 01:00 | IUPUI v Drake | W | 48-80 |
| CBI | 2022/03/21 17:00 | Drake v UNC Wilmington | L | 75-76 |