Stadium: Duane Stadium Round: 1
Home Manager: Dan Curran Away Manager: Chris Villarrial
| NCAAF | 2021/11/13 17:00 | Merrimack Warriors v Saint Francis | W | 6-22 |
| NCAAF | 2019/09/14 16:00 | Saint Francis v Merrimack Warriors | W | 42-14 |
| NCAAF | 2022/11/12 17:00 | Duquesne v Saint Francis | W | 14-51 |
| NCAAF | 2022/11/05 16:30 | Saint Francis v Georgetown Hoyas | W | 38-24 |
| NCAAF | 2022/10/29 16:00 | Saint Francis v Sacred Heart Pion. | W | 44-14 |
| NCAAF | 2022/10/22 17:00 | Stonehill Skyhawks v Saint Francis | W | 13-17 |
| NCAAF | 2022/10/15 17:00 | Saint Francis v Liu | W | 57-7 |
| NCAAF | 2022/10/01 16:00 | Central Conn. State v Saint Francis | W | 13-39 |
| NCAAF | 2022/09/24 18:00 | Saint Francis v Norfolk State | W | 45-26 |
| NCAAF | 2022/09/17 20:00 | Saint Francis v Wagner | W | 27-7 |
| NCAAF | 2022/11/12 17:00 | Merrimack Warriors v Central Conn. State | W | 20-14 |
| NCAAF | 2022/10/29 17:00 | Merrimack Warriors v Stonehill Skyhawks | W | 17-10 |
| NCAAF | 2022/10/22 17:00 | Sacred Heart Pion. v Merrimack Warriors | W | 25-31 |
| NCAAF | 2022/10/15 17:00 | Wagner v Merrimack Warriors | W | 17-54 |
| NCAAF | 2022/10/08 17:00 | Merrimack Warriors v Duquesne | W | 28-21 |
| NCAAF | 2022/10/01 17:00 | Liu v Merrimack Warriors | W | 23-24 |
| NCAAF | 2022/09/24 18:00 | Merrimack Warriors v Delaware State | W | 26-13 |
| NCAAF | 2022/09/16 23:00 | Merrimack Warriors v Harvard Crimson | L | 21-28 |