[17] Jacksonville 27-34 Indianapolis [15] 2022-10-16 17:00
Stadium: Lucas Oil Stadium Round: 1
Home Manager: Frank Reich Away Manager: Doug Pederson
Face à face
| NFL | 2022/09/18 17:00 | Indianapolis v Jacksonville | W | 0-24 |
| NFL | 2022/01/09 18:00 | Indianapolis v Jacksonville | W | 11-26 |
| NFL | 2021/11/14 18:00 | Jacksonville v Indianapolis | L | 17-23 |
| NFL | 2021/01/03 21:25 | Jacksonville v Indianapolis | L | 14-28 |
| NFL | 2020/09/13 17:00 | Indianapolis v Jacksonville | W | 20-27 |
| NFL | 2019/12/29 21:25 | Indianapolis v Jacksonville | W | 20-38 |
| NFL | 2019/11/17 18:00 | Jacksonville v Indianapolis | L | 13-33 |
| NFL | 2018/12/02 18:00 | Indianapolis v Jacksonville | W | 0-6 |
Home History
| NFL | 2022/10/09 17:00 | HOU Texans v Jacksonville | L | 13-6 |
| NFL | 2022/10/02 17:00 | Jacksonville v PHI Eagles | L | 21-29 |
| NFL | 2022/09/25 20:05 | Jacksonville v LA Chargers | W | 38-10 |
| NFL | 2022/09/18 17:00 | Indianapolis v Jacksonville | W | 0-24 |
| NFL | 2022/09/11 17:00 | Jacksonville v Washington | L | 22-28 |
| NFL pré-saison | 2022/08/27 19:00 | Jacksonville v Atlanta | L | 12-28 |
| NFL pré-saison | 2022/08/20 23:00 | PIT Steelers v Jacksonville | L | 16-15 |
| NFL pré-saison | 2022/08/12 23:00 | CLE Browns v Jacksonville | L | 24-13 |
Away History
| NFL | 2022/10/07 00:15 | Indianapolis v Denver | W | 12-9 |
| NFL | 2022/10/02 17:00 | Tennessee Titans v Indianapolis | L | 24-17 |
| NFL | 2022/09/25 17:00 | KC Chiefs v Indianapolis | W | 17-20 |
| NFL | 2022/09/18 17:00 | Indianapolis v Jacksonville | L | 0-24 |
| NFL | 2022/09/11 17:00 | Indianapolis v HOU Texans | D | 20-20 |
| NFL pré-saison | 2022/08/27 23:30 | TB Buccaneers v Indianapolis | W | 10-27 |
| NFL pré-saison | 2022/08/20 17:00 | DET Lions v Indianapolis | L | 27-26 |
| NFL pré-saison | 2022/08/13 20:00 | Indianapolis v BUF Bills | L | 24-27 |