Stadium: Bon Secours Wellness Arena Round: 124
Home Manager: Mike Krzyzewski Away Manager: Tom Izzo
| NCAAB | 2020/12/02 00:30 | Michigan State v Duke | W | 75-69 |
| NCAAB | 2019/12/04 02:30 | Duke v Michigan State | L | 87-75 |
| NCAAB | 2019/03/31 21:05 | Michigan State v Duke | W | 68-67 |
| NCAAB | 2017/11/15 00:00 | Michigan State v Duke | L | 81-88 |
| NCAAB | 2016/11/30 02:30 | Michigan State v Duke | L | 69-78 |
| NCAAB | 2015/04/04 22:09 | Duke v Michigan State | L | 81-61 |
| NCAAB | 2014/11/19 00:00 | Duke v Michigan State | L | 81-71 |
| NCAAB | 2011/11/15 12:00 | Duke v Michigan State | L | 74-69 |
| NCAAB | 2022/03/19 01:40 | Davidson v Michigan State | W | 73-74 |
| NCAAB | 2022/03/12 20:30 | Michigan State v Purdue | L | 70-75 |
| NCAAB | 2022/03/11 23:30 | Michigan State v Wisconsin | W | 69-63 |
| NCAAB | 2022/03/10 23:30 | Maryland v Michigan State | W | 72-76 |
| NCAAB | 2022/03/06 21:30 | Maryland v Michigan State | W | 67-77 |
| NCAAB | 2022/03/04 00:00 | Michigan State v Ohio State | L | 69-80 |
| NCAAB | 2022/03/02 01:30 | Michigan State v Michigan | L | 70-87 |
| NCAAB | 2022/02/26 17:00 | Purdue v Michigan State | W | 65-68 |
| NCAAB | 2022/03/18 23:10 | Cal State Fullerton Titans v Duke | W | 61-78 |
| NCAAB | 2022/03/13 01:30 | Virginia Tech v Duke | L | 82-67 |
| NCAAB | 2022/03/12 00:00 | Miami Florida v Duke | W | 76-80 |
| NCAAB | 2022/03/10 17:00 | Syracuse v Duke | W | 79-88 |
| NCAAB | 2022/03/05 23:00 | North Carolina v Duke | L | 94-81 |
| NCAAB | 2022/03/02 01:00 | Duke v Pittsburgh | W | 86-56 |
| NCAAB | 2022/02/26 23:00 | Duke v Syracuse | W | 97-72 |
| NCAAB | 2022/02/24 00:00 | Duke v Virginie | W | 65-61 |