Stadium: HTC Center
Home Manager: Cliff Ellis Away Manager: Samuel Botta
| NCAAB | 2021/11/24 00:00 | Norfolk State v Regent Royals | L | 95-20 |
| NCAAB | 2021/11/17 00:00 | Delaware State v Regent Royals | L | 84-30 |
| NCAAB | 2021/11/14 00:30 | Hampton v Regent Royals | L | 70-56 |
| NCAAB | 2021/11/12 00:00 | Liberty v Regent Royals | L | 85-24 |
| NCAAB | 2021/11/10 22:00 | Regent Royals v Howard | L | 54-118 |
| NCAAB | 2020/02/13 00:00 | Towson v Regent Royals | L | 71-55 |
| NCAAB | 2020/01/31 23:00 | North Greenville Crusaders v Regent Royals | L | 76-64 |
| NCAAB | 2019/12/19 00:00 | Howard v Regent Royals | L | 105-47 |
| NCAAB | 2021/12/16 00:00 | Coastal Carolina v Methodist Monarchs | W | 102-42 |
| NCAAB | 2021/12/12 19:00 | Wofford v Coastal Carolina | W | 59-60 |
| NCAAB | 2021/12/07 00:00 | Mercer v Coastal Carolina | L | 74-69 |
| NCAAB | 2021/12/04 18:00 | Winthrop v Coastal Carolina | W | 64-74 |
| NCAAB | 2021/12/02 00:00 | South Carolina Gamecocks v Coastal Carolina | W | 56-80 |
| NCAAB | 2021/11/25 01:00 | Toledo v Coastal Carolina | L | 79-70 |
| NCAAB | 2021/11/24 01:00 | Valparaiso v Coastal Carolina | W | 61-64 |
| NCAAB | 2021/11/19 00:00 | Coastal Carolina v UNC Wilmington | L | 53-65 |