[25] Mississippi State 38-28 Lafayette [25] 2019-08-31 16:00
Stadium: Caesars Superdome Round: 1
Home Manager: Billy Napier Away Manager: Joe Moorhead
Home History
| NCAAF | 2019/01/01 17:00 | Iowa v Mississippi State | L | 27-22 |
| NCAAF | 2018/11/23 00:30 | Mississippi State v Ole Miss | W | 35-3 |
| NCAAF | 2018/11/17 17:00 | Arkansas v Mississippi State | W | 6-52 |
| NCAAF | 2018/11/10 20:30 | Mississippi State v Alabama A&M | L | 0-24 |
| NCAAF | 2018/11/03 23:30 | Louisiana Tech v Mississippi State | W | 3-45 |
| NCAAF | 2018/10/27 23:00 | Texas A&M v Mississippi State | W | 13-28 |
| NCAAF | 2018/10/20 23:00 | Mississippi State v LSU | L | 3-19 |
| NCAAF | 2018/10/06 23:30 | Auburn v Mississippi State | W | 9-23 |
Away History
| NCAAF | 2018/12/15 18:30 | Tulane v Lafayette | L | 41-24 |
| NCAAF | 2018/12/01 17:00 | Lafayette v Appalachian State | L | 19-30 |
| NCAAF | 2018/11/24 20:00 | Lafayette v Louisiana-Monroe | W | 31-28 |
| NCAAF | 2018/11/17 22:00 | South Alabama v Lafayette | W | 38-48 |
| NCAAF FCS | 2018/11/17 17:30 | Lehigh v Lafayette | L | 34-3 |
| NCAAF | 2018/11/10 22:00 | Georgia State v Lafayette | W | 22-36 |
| NCAAF | 2018/11/10 17:00 | Lafayette v Army | L | 13-31 |
| NCAAF | 2018/11/03 19:30 | Lafayette v Troy | L | 16-26 |