| Challenger - Quimper | 01/30 13:55 | 25 | Marco Trungelliti v Donati, Matteo | 7-6,6-1 | |
| Challenger Quimper Qual | 01/29 12:40 | 54 | Donati, Matteo v Jahn, Jeremy | 7-5,6-4 | |
| Challenger Quimper Qual | 01/28 13:40 | 46 | Donati, Matteo v Gueydan, Quentin | 6-4,7-6 | |
| Challenger Andria | 11/21 17:25 | 25 | [261] Donati, Matteo v Evgeny Karlovskiy [349] | 6-7,1-6 | |
| Brescia, Italy | 11/15 12:00 | 25 | [136] Stefano Travaglia v Donati, Matteo [263] | 3-6,6-3,6-4 | |
| Brest, France | 10/25 18:00 | 25 | Daniil Medvedev v Donati, Matteo | 4-6,6-1,6-3 | |
| Challenger Ismaning | 10/21 13:45 | 28 | [301] Donati, Matteo v Lorenzo Sonego [265] | 6-7,4-6 | |
| Challenger Ismaning | 10/20 13:45 | 27 | [301] Donati, Matteo v Salvatore Caruso [174] | 7-5,6-3 | |
| Challenger Ismaning | 10/19 11:40 | 26 | [301] Donati, Matteo v Pedro Martinez [262] | 6-1,7-6 | |
| Challenger Ismaning | 10/18 12:45 | 25 | Mats Rosenkranz v Donati, Matteo | 3-6,2-6 | |
| Challenger Ismaning | 10/18 08:00 | 25 | Maximilian Marterer v Donati, Matteo | Cancelled | |
| Challenger Ortisei | 10/14 14:20 | 28 | [344] Donati, Matteo v Lorenzo Sonego [364] | 6-7,6-7 | |
| Challenger Ortisei | 10/13 17:00 | 27 | [344] Donati, Matteo v Seppi, Andreas [85] | 7-6,7-6 | |
| Challenger Ortisei | 10/11 11:00 | 26 | [164] Stefano Napolitano v Donati, Matteo [344] | 6-4,4-6,5-7 | |
| Challenger Ortisei | 10/09 11:00 | 25 | [228] Nicola Kuhn v Donati, Matteo [344] | 7-6,6-7,4-6 | |
| Rome II, Italy | 09/26 09:00 | 25 | [468] Elliot Benchetrit v Donati, Matteo [342] | 6-3,6-4 | |
| Challenger Sibiu | 09/22 07:30 | 26 | [349] Donati, Matteo v Maximilian Marterer [121] | 4-6,5-7 | |
| Challenger Sibiu | 09/19 10:10 | 25 | [349] Donati, Matteo v Robredo, Tommy [150] | 6-1,6-4 | |
| Challenger Sibiu Qual | 09/18 07:00 | 54 | [349] Donati, Matteo v Dimitar Kuzmanov [464] | 6-4,7-5 | |
| Challenger Sibiu Qual | 09/17 07:00 | 46 | Donati, Matteo v Antonescu, Vasile | 6-3,6-1 | |
| Genoa, Italy | 09/08 12:00 | 27 | [438] Donati, Matteo v Garcia-Lopez, Guillermo [123] | 4-6,2-6 | |
| Genoa, Italy | 09/07 11:35 | 26 | [182] Alexey Vatutin v Donati, Matteo [438] | 6-2,4-6,1-6 | |
| Genoa, Italy | 09/05 12:05 | 25 | Andrea Pellegrino v Donati, Matteo | 3-6,4-6 | |
| Challenger Como | 09/01 15:50 | 27 | [342] Corentin Moutet v Donati, Matteo [438] | 3-6,7-5,6-3 | |
| Challenger Como | 08/31 08:30 | 26 | [438] Donati, Matteo v Janowicz, Jerzy [110] | 7-6,7-6 | |
| Challenger Como | 08/29 11:25 | 25 | [438] Donati, Matteo v Hampel, Lenny [371] | 5-7,6-2,6-3 | |
| Challenger Manerbio | 08/21 15:30 | 25 | [313] Steven Diez v Donati, Matteo [361] | 6-3,4-6,6-1 | |
| Cordenons, Italy | 08/15 10:10 | 25 | [418] Munoz-De la Nava, Daniel v Donati, Matteo [349] | 6-3,6-2 | |
| Challenger Biella | 08/02 15:30 | 26 | [307] Donati, Matteo v Filip Krajinovic [140] | 2-6,6-7 | |
| Challenger Biella | 08/01 13:15 | 25 | Ramirez Hidalgo, Ruben v Donati, Matteo | 2-6,2-6 |