| Challenger San Benedetto | 07/18 15:00 | 25 | Vanni, Luca v Virgili, Adelchi | 6-3,7-6 | |
| Challenger Perugia | 07/12 11:40 | 25 | [158] Stefano Napolitano v Vanni, Luca [121] | 4-6,6-4,7-6 | |
| Challenger Recanati | 07/08 19:30 | 28 | [121] Vanni, Luca v Mirza Basic [163] | 7-6,6-7,6-7 | |
| Challenger Recanati | 07/07 19:00 | 27 | [121] Vanni, Luca v Moraing, Mats [332] | 7-6,6-3 | |
| Challenger Recanati | 07/05 19:00 | 26 | [121] Vanni, Luca v Nielsen, Frederik [226] | 6-2,2-6,6-2 | |
| Challenger Recanati | 07/04 15:15 | 25 | [121] Vanni, Luca v Mohamed Safwat [256] | 3-6,6-3,6-4 | |
| Wimbledon Qual | 06/26 13:30 | 44 | [121] Vanni, Luca v Calvin Hemery [205] | 6-2,6-7,11-13 | |
| ATP Halle Qual | 06/17 10:30 | 45 | [77] Ernesto Escobedo v Vanni, Luca [119] | 6-3,7-6 | |
| Challenger - Nottingham | 06/13 14:40 | 25 | [227] Smith, John-Patrick v Vanni, Luca [119] | 4-6,7-6,7-6 | |
| French Open Qual | 05/24 16:00 | 45 | [152] Jozef Kovalik v Vanni, Luca [120] | 6-4,6-4 | |
| French Open Qual | 05/23 09:20 | 44 | [188] Chiudinelli, Marco v Vanni, Luca [120] | 2-6,2-6 | |
| ATP Rome Qual | 05/13 15:00 | 45 | [57] Anderson, Kevin v Vanni, Luca [120] | 4-6,6-1,6-2 | |
| Anning, China | 04/25 03:15 | 25 | [233] Wu, Di v Vanni, Luca [122] | 6-2,6-2 | |
| Challenger Qingdao | 04/18 03:25 | 25 | [122] Vanni, Luca v Alex De Minaur [232] | 7-6,1-6,4-6 | |
| ATP - Marrakech | 04/12 10:00 | 25 | [122] Vanni, Luca v Jiri Vesely [53] | 2-6,3-6 | |
| Marrakech, Morocco, Qualifying | 04/09 11:00 | 46 | [99] Taro Daniel v Vanni, Luca [126] | 7-6,7-6 | |
| Marrakech, Morocco, Qualifying | 04/08 10:00 | 45 | [135] Cervantes, Inigo v Vanni, Luca [126] | 7-6,5-7,5-7 | |
| Challenger Quanzhou | 03/21 03:40 | 25 | [127] Vanni, Luca v Aslan Karatsev [293] | 4-6,3-6 | |
| Challenger - Shenzhen | 03/18 07:00 | 28 | [147] Kavcic, Blaz v Vanni, Luca [139] | 6-2,6-2 | |
| Challenger - Shenzhen | 03/17 05:35 | 27 | Duckhee Lee v Vanni, Luca | 1-6,3-6 | |
| Challenger - Shenzhen | 03/16 04:20 | 26 | [210] Yan Bai v Vanni, Luca [139] | 1-6,2-6 | |
| Challenger - Shenzhen | 03/14 06:30 | 25 | [172] Lopez Perez v Vanni, Luca [139] | 3-6,2-6 | |
| Challenger Zhuhai | 03/10 05:05 | 27 | [163] Ignatik, Uladzimir v Vanni, Luca [139] | 6-4,6-4 | |
| Challenger Zhuhai | 03/08 03:00 | 26 | [170] Jason Jung v Vanni, Luca [139] | 4-6,4-6 | |
| Challenger Zhuhai | 03/06 05:05 | 25 | [201] Hiroki Moriya v Vanni, Luca [138] | 2-6,1-6 | |
| Bergamo, Italy | 02/21 19:50 | 25 | Vanni, Luca v Langer, Nils | 5-7,6-4,3-6 | |
| Challenger - Cherbourg | 02/15 20:50 | 26 | Vanni, Luca v Maximilian Marterer | 6-7,2-6 | |
| Challenger - Cherbourg | 02/13 11:30 | 25 | Vanni, Luca v Mirza Basic | 6-4,6-4 | |
| Challenger Budapest | 02/10 16:20 | 27 | Marton Fucsovics v Vanni, Luca | 6-3,7-5 | |
| Challenger Budapest | 02/09 14:25 | 26 | Skugor, Franko v Vanni, Luca | 4-6,3-6 |