| Challenger Charlottesville | 11/02 22:00 | 26 | Aidan Mayo v Opelka, Reilly | Walkover | |
| Challenger Charlottesville | 11/01 00:15 | 25 | Opelka, Reilly v Tennys Sandgren | 6-4,7-5 | |
| Washington, USA | 08/04 21:45 | 26 | [63] Kyrgios, Nick v Opelka, Reilly [17] | 7-6,6-2 | |
| Washington, USA | 08/03 23:30 | 25 | [82] Denis Kudla v Opelka, Reilly [17] | 7-6,4-6,4-6 | |
| Atlanta, USA | 07/27 23:00 | 26 | Opelka, Reilly v Ilya Ivashka | Cancelled | |
| Wimbledon, London, Great Britain | 06/29 16:30 | 24 | [104] van Rijthoven, Tim v Opelka, Reilly [18] | 6-4,6-7,7-6,7-6 | |
| Wimbledon, London, Great Britain | 06/27 17:40 | 23 | [98] Carlos Taberner v Opelka, Reilly [18] | 6-7,4-6,4-6 | |
| Eastbourne, Great Britain | 06/20 10:00 | 25 | [60] Maxime Cressy v Opelka, Reilly [18] | 6-3,6-1 | |
| London, Great Britain | 06/13 11:00 | 25 | [18] Opelka, Reilly v Alex De Minaur [21] | 4-6,4-6 | |
| French Open, Paris, France | 05/23 09:00 | 23 | [55] Filip Krajinovic v Opelka, Reilly [17] | 7-6,6-2,6-3 | |
| Geneva, Switzerland | 05/20 12:15 | 28 | [18] Opelka, Reilly v Casper Ruud [8] | 6-7,5-7 | |
| Geneva, Switzerland | 05/19 11:30 | 27 | [64] Tallon Griekspoor v Opelka, Reilly [18] | 4-6,6-3,3-6 | |
| Geneva, Switzerland | 05/18 10:00 | 26 | [124] Christopher O'Connell v Opelka, Reilly [18] | 3-6,5-7 | |
| Rome, Italy | 05/09 09:00 | 24 | [361] Stan Wawrinka v Opelka, Reilly [17] | 3-6,7-5,6-2 | |
| ATP - Madrid | 05/03 18:20 | 24 | [17] Opelka, Reilly v Sebastian Korda [30] | 3-6,5-7 | |
| ATP - Munich | 04/28 13:30 | 26 | [17] Opelka, Reilly v Oscar Otte [62] | 6-7,2-6 | |
| ATP - Houston | 04/10 19:00 | 29 | [18] Opelka, Reilly v Isner, John [27] | 6-3,7-6 | |
| ATP - Houston | 04/09 18:00 | 28 | [94] Kyrgios, Nick v Opelka, Reilly [18] | 3-6,5-7 | |
| ATP - Houston | 04/08 17:00 | 27 | [18] Opelka, Reilly v Gijs Brouwer [361] | 6-3,7-5 | |
| ATP - Houston | 04/06 23:00 | 26 | [18] Opelka, Reilly v Mitchell Krueger [161] | 3-6,6-2,6-4 | |
| ATP - Miami | 03/25 21:15 | 24 | [18] Opelka, Reilly v Francisco Cerundolo [103] | Retired | |
| ATP - Indian Wells | 03/16 20:45 | 26 | [4] Rafael Nadal v Opelka, Reilly [17] | 7-6,7-6 | |
| ATP - Indian Wells | 03/14 22:30 | 25 | [17] Opelka, Reilly v Denis Shapovalov [13] | 6-7,6-4,6-4 | |
| ATP - Indian Wells | 03/12 20:50 | 24 | [17] Opelka, Reilly v Lorenzo Musetti [56] | 6-1,6-4 | |
| ATP - Delray Beach | 02/20 20:00 | 29 | [13] Cameron Norrie v Opelka, Reilly [20] | 7-6,7-6 | |
| ATP - Delray Beach | 02/20 01:00 | 28 | John Millman v Opelka, Reilly | 6-7,7-6,6-7 | |
| ATP - Delray Beach | 02/18 23:00 | 27 | [53] Adrian Mannarino v Opelka, Reilly [20] | 6-7,6-3,1-6 | |
| ATP - Delray Beach | 02/17 19:45 | 26 | [141] Sock, Jack v Opelka, Reilly [20] | 7-6,6-7,1-6 | |
| ATP - Dallas | 02/13 19:00 | 29 | [54] Brooksby, Jenson v Opelka, Reilly [23] | 6-7,6-7 | |
| ATP - Dallas | 02/12 22:00 | 28 | [26] Isner, John v Opelka, Reilly [23] | 6-7,6-7 |
Wikipedia - Reilly Opelka
Reilly Opelka, né le à Saint-Joseph dans le Michigan, est un joueur de tennis américain, professionnel depuis 2015.