| Drummondville, Canada | 03/14 19:55 | 26 | [219] Smith, John-Patrick v Roberto Cid Subervi [249] | 7-6,5-7,3-6 | |
| Drummondville, Canada | 03/12 23:05 | 25 | Smith, John-Patrick v Liam Draxl | 6-7,7-5,7-6 | |
| Challenger - Indian Wells | 02/26 20:45 | 25 | [112] Andrey Rublev v Smith, John-Patrick [225] | 6-2,7-5 | |
| Challenger - Indian Wells | 02/25 20:10 | 24 | [225] Smith, John-Patrick v Noah Rubin [152] | 6-7,6-3,6-4 | |
| ATP - Delray Beach | 02/16 21:20 | 64 | [217] Smith, John-Patrick v Darian King [164] | 4-6,6-7 | |
| Open d'Australie | 01/08 23:00 | 44 | [202] Smith, John-Patrick v Bachinger, Matthias [129] | 5-7,3-6 | |
| ATP Brisbane | 12/29 01:15 | 64 | [77] Taro Daniel v Smith, John-Patrick [199] | 3-6,6-4,6-4 | |
| Open d'Australie Playoff Wilcard Australienne | 12/11 23:00 | 27 | [265] Banes, Maverick v Smith, John-Patrick [200] | 6-4,6-7,1-6,6-0,6-2 | |
| Open d'Australie Playoff Wilcard Australienne | 12/09 23:00 | 26 | [467] Beale, Jeremy v Smith, John-Patrick [200] | 2-6,5-7,7-5,3-6 | |
| Challenger Champaign | 11/15 19:55 | 27 | Shane, Ryan v Smith, John-Patrick | 7-5,6-1 | |
| Challenger Champaign | 11/14 18:30 | 26 | [472] Garanganga, Takanyi v Smith, John-Patrick [209] | 3-6,4-6 | |
| Challenger Champaign | 11/12 23:00 | 25 | [303] Denis Yevseyev v Smith, John-Patrick [209] | 3-6,6-7 | |
| Challenger Knoxville | 11/07 00:05 | 25 | [140] Smyczek, Tim v Smith, John-Patrick [202] | 3-6,6-3,6-2 | |
| Challenger Las Vegas | 10/27 17:30 | 28 | [235] Smith, John-Patrick v Rola, Blaz [262] | 3-6,5-7 | |
| Challenger Las Vegas | 10/26 18:00 | 27 | [235] Smith, John-Patrick v Jason Jung [127] | 7-6,6-3 | |
| Challenger Las Vegas | 10/25 18:00 | 26 | [235] Smith, John-Patrick v Cem Ilkel [233] | 6-3,6-1 | |
| Challenger Las Vegas | 10/23 20:10 | 25 | [267] Jelle Sels v Smith, John-Patrick [235] | 7-6,5-7,4-6 | |
| Challenger Las Vegas | 10/23 20:05 | 25 | Opelka, Reilly v Smith, John-Patrick | Cancelled | |
| Challenger Calgary | 10/17 21:40 | 26 | [325] Enzo Couacaud v Smith, John-Patrick [242] | 7-5,7-5 | |
| Challenger Calgary | 10/17 16:00 | 25 | Smith, John-Patrick v Alex Bolt | Cancelled | |
| Challenger Calgary | 10/16 19:45 | 25 | Smith, John-Patrick v Fawcett, Tom | 7-6,7-6 | |
| Challenger Fairfield | 10/09 22:00 | 25 | [158] Fratangelo, Bjorn v Smith, John-Patrick [240] | 3-6,6-2,6-4 | |
| Challenger Stockton | 10/01 21:20 | 25 | [255] Mitchell Krueger v Smith, John-Patrick [236] | 3-6,6-3,6-4 | |
| Challenger Tiburon | 09/28 18:00 | 27 | [104] Granollers, Marcel v Smith, John-Patrick [252] | 6-2,6-3 | |
| Challenger Tiburon | 09/26 18:00 | 26 | [252] Smith, John-Patrick v Fratangelo, Bjorn [175] | 1-6,6-4,6-2 | |
| Challenger Tiburon | 09/25 17:00 | 25 | [252] Smith, John-Patrick v Pedro Martinez [174] | 6-4,6-2 | |
| Challenger Columbus | 09/18 14:00 | 25 | [246] Smith, John-Patrick v Quiroz, Roberto [213] | 6-3,6-7,6-7 | |
| Challenger Chicago | 09/06 17:30 | 26 | [246] Young, Donald v Smith, John-Patrick [220] | 6-3,6-4 | |
| Challenger Chicago | 09/04 15:00 | 25 | [220] Smith, John-Patrick v Roberto Cid Subervi [225] | 2-6,6-1,6-4 | |
| US Open, New York, USA | 08/21 19:10 | 44 | [109] Hubert Hurkacz v Smith, John-Patrick [221] | 6-3,6-2 |