| Olympic Tournament Tokyo, Japan | 07/25 03:25 | 24 | Alexander Zverev v Lu, Yen-Hsun | 6-1,6-3 | |
| Wimbledon, London, Great Britain | 06/29 17:10 | 23 | Marc Polmans v Lu, Yen-Hsun | 6-2,7-5,4-6,6-1 | |
| London, Great Britain | 06/15 16:00 | 25 | Lu, Yen-Hsun v Fabio Fognini | 4-6,6-7 | |
| French Open, Paris, France | 06/01 14:25 | 23 | Diego Schwartzman v Lu, Yen-Hsun | 6-2,6-2,6-3 | |
| ATP - Miami | 03/26 18:55 | 24 | Daniil Medvedev v Lu, Yen-Hsun | 6-2,6-2 | |
| ATP - Miami | 03/24 16:40 | 23 | Querrey, Sam v Lu, Yen-Hsun | 3-6,4-6 | |
| Open d'Australie | 02/08 00:00 | 23 | Opelka, Reilly v Lu, Yen-Hsun | 6-3,7-6,6-3 | |
| ATP Great Ocean Road Open | 01/31 23:30 | 24 | Lu, Yen-Hsun v Aleksandar Vukic | 4-6,5-7 | |
| ATP - Dubaï | 02/25 10:00 | 25 | Lu, Yen-Hsun v Yasutaka Uchiyama | 6-3,1-6,2-6 | |
| Open d'Australie | 01/21 08:25 | 23 | Gaël Monfils v Lu, Yen-Hsun | 6-1,6-4,6-2 | |
| French Open, Paris, France | 05/28 09:00 | - | Bhambri, Yuki v Lu, Yen-Hsun | Cancelled | |
| Challenger - Busan | 05/15 04:25 | 25 | [108] Lu, Yen-Hsun v Yosuke Watanuki [347] | 1-6,2-6 | |
| Challenger Gimcheon | 05/08 06:55 | - | Duckhee Lee v Lu, Yen-Hsun | Cancelled | |
| Challenger Seoul | 05/03 01:30 | 26 | [232] Lloyd Harris v Lu, Yen-Hsun [109] | Retired | |
| Challenger Seoul | 04/30 04:55 | 25 | [347] Banes, Maverick v Lu, Yen-Hsun [109] | 4-6,1-6 | |
| Ningbo, China | 10/21 05:00 | 28 | [60] Lu, Yen-Hsun v Taro Daniel [119] | Retired | |
| Ningbo, China | 10/20 05:25 | 27 | [60] Lu, Yen-Hsun v Polansky, Peter [130] | 6-2,6-3 | |
| Ningbo, China | 10/18 03:00 | 26 | [60] Lu, Yen-Hsun v Tatsuma Ito [154] | 6-2,6-3 | |
| Ningbo, China | 10/16 06:00 | 25 | [61] Lu, Yen-Hsun v Soeda, Go [143] | 6-3,4-6,6-4 | |
| ATP Shanghai Qual | 10/08 04:00 | 46 | [63] Lu, Yen-Hsun v Stefanos Tsitsipas [115] | 7-5,6-7,4-6 | |
| ATP Shanghai Qual | 10/07 05:30 | 45 | Lu, Yen-Hsun v Rigele Te | 7-5,6-3 | |
| ATP Tokyo | 10/05 04:25 | 26 | [30] Richard Gasquet v Lu, Yen-Hsun [63] | 6-0,7-6 | |
| ATP Tokyo | 10/03 07:30 | 25 | [116] Taro Daniel v Lu, Yen-Hsun [63] | 1-6,3-6 | |
| Chengdu, Chine | 09/29 12:50 | 27 | [63] Lu, Yen-Hsun v Baghdatis, Marcos [113] | 3-6,2-6 | |
| Chengdu, Chine | 09/28 05:00 | 26 | [37] Andrey Rublev v Lu, Yen-Hsun [63] | 2-6,1-6 | |
| Chengdu, Chine | 09/26 05:00 | 25 | [63] Lu, Yen-Hsun v Ymer, Mikael [328] | 6-2,6-3 | |
| Challenger Shanghai | 09/17 04:50 | 29 | [62] Lu, Yen-Hsun v Yibing Wu [496] | Retired | |
| Challenger Shanghai | 09/16 03:00 | 28 | [62] Lu, Yen-Hsun v Zhang, Ze [234] | 6-1,6-2 | |
| Challenger Shanghai | 09/15 02:30 | 27 | [62] Lu, Yen-Hsun v Mohamed Safwat [211] | 6-2,7-5 | |
| Challenger Shanghai | 09/13 02:30 | 26 | [62] Lu, Yen-Hsun v Luke Saville [375] | 6-4,6-4 |