| Newport, USA | 07/17 18:00 | 26 | [113] Guido Andreozzi v Zverev, Mischa [209] | 4-6,4-6 | |
| Newport, USA | 07/16 21:30 | 25 | [209] Zverev, Mischa v Smyczek, Tim [221] | 6-3,7-6 | |
| Wimbledon, London, Great Britain | 07/01 11:25 | 23 | [221] Darcis, Steve v Zverev, Mischa [213] | 6-2,6-4,6-4 | |
| ATP Halle | 06/16 11:10 | 164 | [72] Seppi, Andreas v Zverev, Mischa [114] | 6-3,6-2 | |
| ATP Halle | 06/15 11:45 | 64 | [114] Zverev, Mischa v Lloyd Harris [87] | 6-3,5-7,6-4 | |
| Stuttgart, Germany | 06/10 09:00 | 25 | [114] Zverev, Mischa v Tsonga, Jo-Wilfried [79] | 3-6,0-6 | |
| Open de France | 05/27 10:40 | 23 | [102] Zverev, Mischa v Richard Gasquet [39] | 3-6,4-6,3-6 | |
| ATP - Genève | 05/19 15:45 | 25 | [101] Zverev, Mischa v Londero, Juan Ignacio [73] | 4-6,4-6 | |
| ATP - Madrid | 05/04 17:00 | 45 | [95] Zverev, Mischa v Opelka, Reilly [59] | 6-7,6-7 | |
| ATP - Munich | 04/30 12:45 | 25 | [26] Pella, Guido v Zverev, Mischa [95] | 6-2,6-1 | |
| ATP - Barcelone | 04/23 11:50 | 24 | [155] FERRER D. v Zverev, Mischa [96] | 6-3,6-1 | |
| ATP - Monte-Carlo | 04/13 09:00 | 45 | [72] Zverev, Mischa v Ocleppo, Julian [193] | 6-7,6-7 | |
| ATP - Marrakech | 04/08 14:45 | 25 | [75] Taro Daniel v Zverev, Mischa [72] | 6-3,6-0 | |
| ATP - Miami | 03/22 16:30 | 24 | [19] Nikoloz Basilashvili v Zverev, Mischa [75] | 6-3,6-2 | |
| ATP - Miami | 03/20 20:00 | 23 | [255] Nicola Kuhn v Zverev, Mischa [75] | Retired | |
| ATP - Indian Wells | 03/07 19:00 | 23 | [50] Martin Klizan v Zverev, Mischa [75] | 6-1,6-4 | |
| ATP - Acapulco | 02/27 01:35 | 25 | [2] Rafael Nadal v Zverev, Mischa [76] | 6-3,6-3 | |
| ATP - Montpellier | 02/04 19:55 | 25 | Zverev, Mischa v Chardy, Jérémy | Cancelled | |
| Open d'Australie | 01/15 06:05 | 23 | [149] Alexei Popyrin v Zverev, Mischa [70] | 7-5,7-6,6-4 | |
| Basel, Switzerland | 10/20 11:30 | 64 | [90] Marius Copil v Zverev, Mischa [71] | 7-5,7-5 | |
| Moscow, Russia | 10/16 11:15 | 25 | [57] Benoit Paire v Zverev, Mischa [71] | 7-6,2-6,6-1 | |
| Shanghai, Chine | 10/07 05:55 | 24 | [47] Nicolas Jarry v Zverev, Mischa [69] | 6-4,3-6,7-6 | |
| Pékin, Chine | 10/02 06:05 | 25 | [69] Zverev, Mischa v Filip Krajinovic [36] | 1-6,4-6 | |
| Chengdu, Chine | 09/25 05:00 | 25 | [69] Zverev, Mischa v Bemelmans, Ruben [114] | Retired | |
| Metz, France | 09/17 18:05 | 25 | [63] Zverev, Mischa v Maden, Yannick [120] | 5-7,6-4,1-6 | |
| Metz, France | 09/17 17:20 | - | Zverev, Mischa v Kohlschreiber, Philipp | Cancelled | |
| US Open, New York, USA | 08/27 18:05 | 23 | [48] Zverev, Mischa v Taylor Fritz [74] | 6-4,6-2,4-6,6-7,2-6 | |
| Cincinnati, USA | 08/15 20:05 | 25 | [44] Zverev, Mischa v Grigor Dimitrov [5] | 6-7,5-7 | |
| Cincinnati, USA | 08/14 20:35 | 24 | [24] Damir Dzumhur v Zverev, Mischa [44] | 3-6,4-6 | |
| Washington, USA | 08/02 23:45 | 26 | [3] Alexander Zverev v Zverev, Mischa [42] | 6-3,7-5 |