[7] Santos de Guapiles 0-2 Guadalupe FC [10] 2018-10-13 21:00
Weather: Rainy Stadium: Estadio Ebal Rodriguez Pitch: Artificial Turf Round: 16
Face à face
| Costa Rica - Primera Division | 2018/08/19 21:00 | Guadalupe FC v Santos de Guapiles | L | 2-1 |
| Costa Rica - Primera Division | 2018/02/18 21:00 | Guadalupe FC v Santos de Guapiles | W | 2-3 |
| Costa Rica - Primera Division | 2018/01/07 21:00 | Santos de Guapiles v Guadalupe FC | D | 1-1 |
| Costa Rica - Primera Division | 2017/10/15 19:00 | Guadalupe FC v Santos de Guapiles | W | 0-4 |
| Costa Rica - Primera Division | 2017/08/31 02:00 | Santos de Guapiles v Guadalupe FC | L | 0-2 |