[6] Caciques Humacao 86-94 Santurce [4] 2022-05-22 22:00
Stadium: Emilio E. Huyke Coliseum Round: 1
Face à face
| Puerto Rico - Superior National | 2021/10/06 00:00 | Santurce v Caciques Humacao | W | 88-92 |
| Puerto Rico - Superior National | 2021/09/17 00:00 | Caciques Humacao v Santurce | L | 90-100 |
| Puerto Rico - Superior National | 2021/08/17 00:00 | Caciques Humacao v Santurce | L | 83-98 |
| Puerto Rico - Superior National | 2021/08/14 00:00 | Santurce v Caciques Humacao | L | 99-97 |