[4] Oriente Petrolero 1-3 Union Santa Fe [3] 2022-04-12 22:15
Stadium: Stade Ramon Tahuichi Aguilera Round: 2
Referee: Marlon Gregorio Vera Solis Home Manager: Erwin Sanchez Away Manager: Gustavo Munua
Home History
| Bolivie - Tournoi d'ouverture | 2022/04/09 23:30 | Oriente Petrolero v Nacional Potosi | W | 4-2 |
| Copa Sudamericana | 2022/04/06 22:15 | Fluminense v Oriente Petrolero | L | 3-0 |
| Bolivie - Tournoi d'ouverture | 2022/04/02 19:00 | Real Santa Cruz v Oriente Petrolero | L | 2-1 |
| Copa Sudamericana | 2022/03/15 22:15 | Oriente Petrolero v Royal Pari FC | W | 3-0 |
| Bolivie - Tournoi d'ouverture | 2022/03/13 00:00 | Oriente Petrolero v Blooming | L | 1-2 |
| Copa Sudamericana | 2022/03/08 22:15 | Royal Pari FC v Oriente Petrolero | W | 2-3 |
| Bolivie - Tournoi d'ouverture | 2022/03/03 23:30 | Oriente Petrolero v Universitario de Sucre | W | 1-0 |
| Bolivie - Tournoi d'ouverture | 2022/02/26 19:00 | Palmaflor v Oriente Petrolero | L | 2-1 |
Away History
| Liga Profesional | 2022/04/09 17:00 | Union Santa Fe v Newells | W | 1-0 |
| Copa Sudamericana | 2022/04/06 22:15 | Union Santa Fe v Juniors | D | 1-1 |
| Liga Profesional | 2022/04/01 22:00 | Patronato Parana v Union Santa Fe | L | 2-1 |
| Argentine - Coupe d'Argentine | 2022/03/23 22:10 | Union Santa Fe v Sportivo Las Parejas | W | 5-4 |
| Liga Profesional | 2022/03/19 21:30 | Colón v Union Santa Fe | D | 0-0 |
| Liga Profesional | 2022/03/13 20:00 | Union Santa Fe v Banfield | W | 2-1 |
| Liga Profesional | 2022/03/04 22:15 | Union Santa Fe v CA Platense | W | 1-0 |
| Liga Profesional | 2022/02/27 20:00 | Sarmiento v Union Santa Fe | L | 2-1 |