Face à face
| Japon - NPB | 2022/03/29 09:30 | Seibu Lions v Nippon Ham Fighters | W | 4-0 |
| Japon - NPB - Exhibition | 2022/03/16 04:00 | Nippon Ham Fighters v Seibu Lions | W | 5-7 |
| Japon - NPB - Exhibition | 2022/03/15 09:00 | Nippon Ham Fighters v Seibu Lions | W | 1-4 |
| Japon - NPB | 2021/10/26 09:00 | Seibu Lions v Nippon Ham Fighters | L | 0-1 |
| Japon - NPB | 2021/10/20 08:45 | Nippon Ham Fighters v Seibu Lions | W | 5-7 |
| Japon - NPB | 2021/10/19 08:45 | Nippon Ham Fighters v Seibu Lions | L | 6-2 |
| Japon - NPB | 2021/10/14 09:00 | Seibu Lions v Nippon Ham Fighters | W | 3-0 |
| Japon - NPB | 2021/10/13 09:00 | Seibu Lions v Nippon Ham Fighters | L | 2-10 |
Home History
| Japon - NPB | 2022/03/29 09:30 | Seibu Lions v Nippon Ham Fighters | W | 4-0 |
| Japon - NPB | 2022/03/27 05:00 | Orix Buffaloes v Seibu Lions | W | 6-7 |
| Japon - NPB | 2022/03/26 05:00 | Orix Buffaloes v Seibu Lions | W | 0-5 |
| Japon - NPB | 2022/03/25 09:00 | Orix Buffaloes v Seibu Lions | L | 6-0 |
| Japon - NPB - Exhibition | 2022/03/21 04:00 | Yakult Swallows v Seibu Lions | W | 1-4 |
| Japon - NPB - Exhibition | 2022/03/20 04:00 | Yakult Swallows v Seibu Lions | L | 2-1 |
| Japon - NPB - Exhibition | 2022/03/19 04:00 | Yakult Swallows v Seibu Lions | W | 5-6 |
| Japon - NPB - Exhibition | 2022/03/18 04:00 | Yakult Swallows v Seibu Lions | D | 1-1 |
Away History
| Japon - NPB | 2022/03/29 09:30 | Seibu Lions v Nippon Ham Fighters | L | 4-0 |
| Japon - NPB | 2022/03/27 04:00 | Nippon Ham Fighters v Softbank Hawks | L | 4-6 |
| Japon - NPB | 2022/03/26 05:00 | Nippon Ham Fighters v Softbank Hawks | L | 3-6 |
| Japon - NPB | 2022/03/25 09:30 | Nippon Ham Fighters v Softbank Hawks | L | 1-4 |
| Japon - NPB - Exhibition | 2022/03/20 04:00 | Yokohama Bay Stars v Nippon Ham Fighters | W | 1-4 |
| Japon - NPB - Exhibition | 2022/03/19 05:00 | Yokohama Bay Stars v Nippon Ham Fighters | W | 4-6 |
| Japon - NPB - Exhibition | 2022/03/18 09:00 | Yokohama Bay Stars v Nippon Ham Fighters | L | 6-1 |
| Japon - NPB - Exhibition | 2022/03/16 04:00 | Nippon Ham Fighters v Seibu Lions | L | 5-7 |