[6] Club Nacional Asuncion 0-2 Guairena [7] 2021-08-20 23:30
Stadium: Estadio Arsenio Erico Round: 6
Referee: Julio Cesar Quintana Rodriguez Home Manager: Rodrigo Lopez Away Manager: Troadio Daniel Duarte
Face à face
| Paraguay - Division Profesional | 2021/04/30 22:00 | Club Nacional Asuncion v Guairena | L | 1-3 |
| Paraguay - Division Profesional | 2021/03/01 21:30 | Guairena v Club Nacional Asuncion | L | 1-0 |
| Paraguay - Division Profesional | 2020/11/22 21:30 | Club Nacional Asuncion v Guairena | D | 0-0 |
| Paraguay - Division Profesional | 2020/08/07 20:00 | Guairena v Club Nacional Asuncion | D | 0-0 |
| Paraguay - Division Profesional | 2020/01/18 21:00 | Club Nacional Asuncion v Guairena | W | 3-0 |
Home History
| Paraguay - Division Profesional | 2021/08/13 23:45 | River Plate v Club Nacional Asuncion | L | 1-0 |
| Paraguay - Division Profesional | 2021/08/07 21:15 | Club Nacional Asuncion v Libertad Asuncion | W | 1-0 |
| Paraguay - Division Profesional | 2021/07/31 21:15 | Sportivo Luqueno v Club Nacional Asuncion | L | 2-1 |
| Paraguay - Division Profesional | 2021/07/24 22:30 | Club Nacional Asuncion v Guarani Asuncion | D | 1-1 |
| Paraguay - Division Profesional | 2021/07/17 21:15 | 12 de Octubre v Club Nacional Asuncion | D | 2-2 |
| Paraguay - Division Profesional | 2021/05/31 00:00 | 12 de Octubre v Club Nacional Asuncion | D | 2-2 |
| Paraguay - Division Profesional | 2021/05/24 00:00 | Club Nacional Asuncion v River Plate | L | 0-1 |
| Paraguay - Division Profesional | 2021/05/17 22:00 | Club Nacional Asuncion v Olimpia Asuncion | W | 2-1 |
Away History
| Paraguay - Division Profesional | 2021/08/13 21:30 | Guairena v Sol de America | D | 1-1 |
| Paraguay - Division Profesional | 2021/08/07 23:30 | Cerro Porteno v Guairena | L | 2-0 |
| Paraguay - Division Profesional | 2021/08/01 23:15 | Olimpia Asuncion v Guairena | W | 0-2 |
| Paraguay - Division Profesional | 2021/07/25 21:15 | Guairena v River Plate | L | 1-2 |
| Paraguay - Division Profesional | 2021/07/18 23:30 | Libertad Asuncion v Guairena | D | 0-0 |
| Paraguay - Division Profesional | 2021/05/28 21:45 | Sol de America v Guairena | D | 0-0 |
| Paraguay - Division Profesional | 2021/05/21 23:00 | Guairena v Guarani Asuncion | D | 0-0 |
| Paraguay - Division Profesional | 2021/05/16 00:00 | 12 de Octubre v Guairena | D | 1-1 |