[6] Olimpia Asuncion 1-3 River Plate [7] 2021-07-18 21:15
Stadium: Stade Manuel Ferreira Round: 1
Referee: Carlos P. Benitez Home Manager: Sergio Daniel Orteman Rodriguez Away Manager: Celso Ayala
Face à face
| Paraguay - Division Profesional | 2021/05/30 21:45 | River Plate v Olimpia Asuncion | W | 1-2 |
| Paraguay - Division Profesional | 2021/03/21 23:30 | Olimpia Asuncion v River Plate | W | 5-1 |
| Paraguay - Division Profesional | 2020/11/28 22:00 | Olimpia Asuncion v River Plate | W | 3-1 |
| Paraguay - Division Profesional | 2020/09/11 23:30 | River Plate v Olimpia Asuncion | W | 0-4 |
| Paraguay - Division Profesional | 2020/03/08 23:15 | Olimpia Asuncion v River Plate | D | 1-1 |
| Paraguay - Division Profesional | 2019/10/19 23:15 | River Plate v Olimpia Asuncion | W | 0-1 |
| Paraguay - Division Profesional | 2019/07/27 22:00 | Olimpia Asuncion v River Plate | W | 2-1 |
| Paraguay - Division Profesional | 2019/05/14 19:00 | River Plate v Olimpia Asuncion | D | 2-2 |
Home History
| Copa Libertadores - Qualif. | 2021/07/16 00:30 | Olimpia Asuncion v Internacional | D | 0-0 |
| Paraguay - Division Profesional | 2021/05/30 21:45 | River Plate v Olimpia Asuncion | W | 1-2 |
| Copa Libertadores | 2021/05/26 22:00 | Olimpia Asuncion v Deportivo Tachira | W | 6-2 |
| Paraguay - Division Profesional | 2021/05/23 21:45 | Olimpia Asuncion v Sportivo Luqueno | W | 4-1 |
| Copa Libertadores | 2021/05/21 00:00 | Olimpia Asuncion v Internacional | L | 0-1 |
| Paraguay - Division Profesional | 2021/05/17 22:00 | Club Nacional Asuncion v Olimpia Asuncion | L | 2-1 |
| Copa Libertadores | 2021/05/14 00:00 | Always Ready v Olimpia Asuncion | W | 1-2 |
| Paraguay - Division Profesional | 2021/05/09 21:45 | Olimpia Asuncion v Sol de America | D | 3-3 |
Away History
| Paraguay - Division Profesional | 2021/05/30 21:45 | River Plate v Olimpia Asuncion | L | 1-2 |
| Copa Sudamericana | 2021/05/27 00:30 | Corinthians v River Plate | L | 4-0 |
| Paraguay - Division Profesional | 2021/05/24 00:00 | Club Nacional Asuncion v River Plate | W | 0-1 |
| Copa Sudamericana | 2021/05/18 22:15 | River Plate v Penarol | W | 2-1 |
| Paraguay - Division Profesional | 2021/05/16 21:45 | River Plate v Cerro Porteno | D | 1-1 |
| Copa Sudamericana | 2021/05/14 00:30 | River Plate v Sport Huancayo | W | 2-1 |
| Paraguay - Division Profesional | 2021/05/10 00:00 | Guairena v River Plate | D | 0-0 |
| Copa Sudamericana | 2021/05/07 00:30 | Penarol v River Plate | L | 3-0 |