Round: 25 Ground: Clay
| ITF W60 Saint-Gaudens | 2021/05/11 16:50 | Droguet, Aubane v Elena-Gabriela Ruse | 0-6,7-6,3-6 |
| ITF W25 Prague | 2021/05/08 09:00 | Dalma Galfi v Elena-Gabriela Ruse | 6-4,6-4 |
| ITF W25 Prague | 2021/05/07 08:55 | Elena-Gabriela Ruse v Cagla Buyukakcay | 6-2,6-3 |
| ITF W25 Prague | 2021/05/06 09:50 | Elena-Gabriela Ruse v Paula Ormaechea | 6-4,6-1 |
| ITF W25 Prague | 2021/05/04 09:50 | Elena-Gabriela Ruse v En Shuo Liang | 5-7,6-4,6-1 |
| ITF W60 Zagreb | 2021/04/29 08:00 | Jessica Pieri v Elena-Gabriela Ruse | 4-6,7-6,6-3 |
| ITF W60 Zagreb | 2021/04/27 12:05 | Elena-Gabriela Ruse v Greet Minnen | 6-3,6-1 |
| Billie Jean King Cup | 2021/04/17 11:00 | Elena-Gabriela Ruse v Jasmine Paolini | 1-6,6-3,6-4 |
| ITF W60 Saint-Gaudens | 2021/05/12 12:40 | Yerolymos, Margot v Di Giuseppe, Martina | 6-2,2-6,6-3 |
| ITF W25 Prague | 2021/05/06 13:05 | Di Giuseppe, Martina v Daniela Seguel | 3-6,0-6 |
| ITF W25 Prague | 2021/05/05 07:55 | Di Giuseppe, Martina v Mariam Bolkvadze | 6-4,3-6,6-3 |
| ITF W60 Zagreb | 2021/04/28 09:40 | Jessica Pieri v Di Giuseppe, Martina | 2-6,6-2,6-2 |
| ITF W60 Oeiras | 2021/04/14 14:45 | Di Giuseppe, Martina v Despina Papamichail | 1-6,4-6 |
| ITF W60 Bellinzona | 2021/04/07 09:00 | Di Giuseppe, Martina v Ekaterine Gorgodze | 1-6,4-6 |
| Grenoble, Singles Qualifying W-ITF-FRA-04A | 2021/02/09 08:50 | Cristina Bucsa v Di Giuseppe, Martina | 6-4,6-4 |
| ITF W60 Andrezieux-Boutheon | 2021/01/27 12:35 | Di Giuseppe, Martina v Rebecca Sramkova | 4-6,4-6 |