[3] Juniors 1-1 River Plate [2] 2021-05-13 00:00
Stadium: Estadio Romelio Martinez Round: 4
Referee: Esteban Ostojich Home Manager: Luis Perea Away Manager: Marcelo Gallardo
Face à face
| Copa Libertadores | 2021/04/29 00:00 | River Plate v Juniors | L | 2-1 |
Home History
| Copa Libertadores | 2021/05/07 00:00 | Juniors v Fluminense | D | 1-1 |
| Colombie - Primera A | 2021/05/02 18:00 | Independiente Santa Fe v Juniors | D | 0-0 |
| Copa Libertadores | 2021/04/29 00:00 | River Plate v Juniors | L | 2-1 |
| Colombie - Primera A | 2021/04/25 20:30 | Juniors v Independiente Santa Fe | W | 3-1 |
| Copa Libertadores | 2021/04/23 02:00 | Juniors v Independiente Santa Fe | D | 1-1 |
| Copa Libertadores - Qualif. | 2021/04/16 00:30 | Juniors v Bolivar | W | 3-0 |
| Colombie - Primera A | 2021/04/11 22:40 | Deportivo Pasto v Juniors | D | 0-0 |
| Copa Libertadores - Qualif. | 2021/04/09 00:30 | Bolivar v Juniors | L | 2-1 |
Away History
| Argentine - Copa de la Liga Profesional | 2021/05/09 17:30 | River Plate v CA Aldosivi | W | 4-1 |
| Copa Libertadores | 2021/05/07 00:00 | Independiente Santa Fe v River Plate | D | 0-0 |
| Argentine - Copa de la Liga Profesional | 2021/05/02 19:30 | Banfield v River Plate | L | 1-0 |
| Copa Libertadores | 2021/04/29 00:00 | River Plate v Juniors | W | 2-1 |
| Argentine - Copa de la Liga Profesional | 2021/04/25 21:00 | River Plate v San Lorenzo | L | 1-2 |
| Copa Libertadores | 2021/04/22 22:00 | Fluminense v River Plate | D | 1-1 |
| Argentine - Copa de la Liga Profesional | 2021/04/17 00:30 | Central Cordoba v River Plate | W | 0-5 |
| Argentine - Copa de la Liga Profesional | 2021/04/12 00:00 | River Plate v Colón | W | 3-2 |